Altered Integration of Matrilin-3 into Cartilage Extracellular Matrix in the Absence of Collagen IX
نویسندگان
چکیده
منابع مشابه
Altered integration of matrilin-3 into cartilage extracellular matrix in the absence of collagen IX.
The matrilins are a family of four noncollagenous oligomeric extracellular matrix proteins with a modular structure. Matrilins can act as adapters which bridge different macromolecular networks. We therefore investigated the effect of collagen IX deficiency on matrilin-3 integration into cartilage tissues. Mice harboring a deleted Col9a1 gene lack synthesis of a functional protein and produce c...
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Cartilage Matrix Assembly: Evidence for Binding of Matrilin-3 to Collagens Ix and Xi
Introduction Matrilin-3 is a member of the newly defined matrilin family of extracellular matrix proteins. All matrilin family members consist of one or two von Willebrand factor type A-like domain(s), 1-10 epidermal growth factor-like domain(s) and a C-terminal coiled-coil oligomerization domain (1). Matrilin-1 (also known as CMP) and matrilin-3 are prominent matrix components of growth cartil...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2005
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.25.23.10465-10478.2005